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SigTuple vs Tempus

Side-by-side on valuation, funding, investors, founders & more

Comparison updated: April 2026

Tempus is valued at $8.1B — more than 3x SigTuple's N/A.

Head-to-Head Verdict

Tempus leads on 3 of 4 metrics

SigTuple

0 wins

-Funding
-Awaira Score
-Team Size
=Experience

Tempus

3 wins

+Funding
+Awaira Score
+Team Size
=Experience

Key Numbers

Valuation
N/A
$8.1B
Total Funding
$20M
$1.1B
Awaira Score
60/100
84/100
Employees
100-500
2500
Founded
2015
2015
Stage
Series B
Public
SigTupleTempus
SigTuple logo
SigTuple

🇮🇳 India · Rohit Kumar Pandey

Series BAI HealthcareEst. 2015

Valuation

N/A

Total Funding

$20M

Awaira Score60/100

100-500 employees

Full SigTuple Profile →
Winner
Tempus logo
Tempus

🇺🇸 United States · Eric Lefkofsky

PublicAI HealthcareEst. 2015

Valuation

$8.1B

Total Funding

$1.1B

Awaira Score84/100

2500 employees

Full Tempus Profile →
Market Context

Both companies compete in the AI Healthcare space, though from different geographies — SigTuple in India and Tempus in United States. Different stages (Series B vs Public) mean these companies face fundamentally different operational priorities.

🔬

Analyst Summary

Built from real data · Updated April 2026

Companies

In the AI Healthcare market, SigTuple and Tempus represent two distinct approaches. SigTuple develops AI-powered automated pathology solutions that digitize and analyze microscopy slides for blood, urine, sputum, and semen samples, enabling high-throughput diagnostic testing without the constant presence of trained pathologists. Tempus is an AI-driven oncology and precision medicine company founded in 2015 that utilizes machine learning and data analysis to improve cancer treatment outcomes.

Funding & Valuation

Only Tempus has a public valuation on record ($8.1B); SigTuple's has not been disclosed. Tempus has amassed $1.1B in total funding, far exceeding SigTuple's $20M.

Growth Stage

Both companies were founded in 2015, giving them equivalent market tenure. Growth stages differ: SigTuple (Series B) versus Tempus (Public), a distinction that matters for both deal structure and competitive positioning. On headcount, SigTuple reports 100-500 employees and Tempus reports 2500.

Geography & Outlook

SigTuple operates out of 🇮🇳 India while Tempus is based in 🇺🇸 United States, giving each a distinct home-market advantage. A 24-point gap on the Awaira Score (Tempus: 84, SigTuple: 60) signals a clear difference in overall company strength. Under Rohit Kumar Pandey and Eric Lefkofsky respectively, both companies continue to chart aggressive growth paths.

Funding Velocity

SigTuple

Total Rounds3
Avg. Round Size$6.7M
Funding Span2.7 yrs

Tempus

Total Rounds5
Avg. Round Size$90M
Funding Span5.5 yrs

Funding History

SigTuple has completed 3 funding rounds, while Tempus has gone through 5. SigTuple's most recent round was a Series B of $14M, compared to Tempus's IPO. SigTuple is at Series B while Tempus is at Public — different points in their growth trajectory.

Team & Scale

Tempus has the bigger team at roughly 2500 people — 25x the size of SigTuple's 100-500. Both companies were founded in 2015. Geographically, they're in different markets — SigTuple operates out of India and Tempus from United States.

Metrics Comparison

MetricSigTupleTempus
💰Valuation
N/A
$8.1B
📈Total Funding
$20M
$1.1BWINS
📅Founded
2015
2015
🚀Stage
Series B
Public
👥Employees
100-500
2500
🌍Country
India
United States
🏷️Category
AI Healthcare
AI Healthcare
Awaira Score
60
84WINS

Key Differences

📈

Funding gap: Tempus has raised $1B more ($1.1B vs $20M)

🚀

Growth stage: SigTuple is at Series B vs Tempus at Public

👥

Team size: SigTuple has 100-500 employees vs Tempus's 2500

🌍

Market base: 🇮🇳 SigTuple (India) vs 🇺🇸 Tempus (United States)

⚔️

Direct competitors: Both operate in the AI Healthcare market segment

Awaira Score: Tempus scores 84/100 vs SigTuple's 60/100

Which Should You Choose?

Use these signals to make the right call

SigTuple logo

Choose SigTuple if…

  • India-based for regional compliance or proximity
  • SigTuple develops AI-powered automated pathology solutions that digitize and analyze microscopy slides for blood, urine, sputum, and semen samples, enabling high-throughput diagnostic testing without the constant presence of trained pathologists
Tempus logo

Choose Tempus if…

Top Pick
  • Higher Awaira Score — 84/100 vs 60/100
  • More established by valuation ($8.1B)
  • Stronger investor backing — raised $1.1B
  • United States-based for regional compliance or proximity
  • Tempus is an AI-driven oncology and precision medicine company founded in 2015 that utilizes machine learning and data analysis to improve cancer treatment outcomes

Funding History

SigTuple raised $20M across 3 rounds. Tempus raised $1.1B across 5 rounds.

SigTuple

Series B

Feb 2018

$14M

Series A

Oct 2016

$4.4M

Seed

Jun 2015

$1.6M

Tempus

IPO

Jul 2021

Series D

Jan 2021

$175M

Series C

Jan 2019

$110M

Series B

Jan 2017

$45M

Series A

Jan 2016

$30M

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FAQ — SigTuple vs Tempus

Is SigTuple bigger than Tempus?
Tempus has a disclosed valuation of $8.1B, while SigTuple's valuation is not publicly available, making a direct size comparison difficult. Tempus employs 2500 people.
Which company raised more funding — SigTuple or Tempus?
Tempus has raised more in total funding at $1.1B, compared to SigTuple's $20M — a gap of $1B. Combined, the two companies have completed 8 known funding rounds.
Which company has a higher Awaira Score?
Tempus leads with an Awaira Score of 84/100, while SigTuple sits at 60/100. That 24-point gap reflects real differences in funding, scale, and traction — it's not a vanity metric.
Who founded SigTuple vs Tempus?
SigTuple was founded by Rohit Kumar Pandey in 2015. Tempus was founded by Eric Lefkofsky in 2015. Visit each company's profile on Awaira for a full founder biography.
What does SigTuple do vs Tempus?
SigTuple: SigTuple develops AI-powered automated pathology solutions that digitize and analyze microscopy slides for blood, urine, sputum, and semen samples, enabling high-throughput diagnostic testing without the constant presence of trained pathologists. The company's AI-Minth platform uses robotic sample preparation, high-resolution imaging, and deep learning analysis to deliver diagnostic-grade results.\n\nThe company raised approximately $20M in Series B funding and has deployed its automated microscopy systems at diagnostic labs, hospitals, and blood banks across India, processing millions of diagnostic samples. SigTuple has received regulatory approvals for its diagnostic AI products and has established partnerships with major diagnostic laboratory chains.\n\nIndia faces a severe shortage of qualified pathologists relative to population, creating an acute need for AI-assisted diagnostic automation. SigTuple's approach of combining hardware, robotics, and AI in an integrated system addresses the complete diagnostic workflow rather than just the software layer, creating higher deployment barriers but also higher switching costs and stronger network effects from accumulated diagnostic data. Tempus: Tempus is an AI-driven oncology and precision medicine company founded in 2015 that utilizes machine learning and data analysis to improve cancer treatment outcomes. The platform aggregates and analyzes vast datasets including clinical data, imaging, molecular information, and outcomes to identify personalized treatment strategies for cancer patients. Tempus's core technology uses artificial intelligence to match patient-specific tumor characteristics with optimal therapeutic options, enabling oncologists to make data-informed treatment decisions. The company operates primarily in the United States and serves hospitals, health systems, and oncology practices through its cloud-based platform. Its applications span multiple cancer types including lung, colorectal, breast, and ovarian cancers. Tempus has secured $1.3 billion in total funding and achieved a valuation of $8.1 billion, reflecting significant investor confidence in precision oncology. The company went public, transitioning from private to public markets. Tempus competes with other AI health platforms and precision medicine companies like Foundation Medicine and others focused on genomic analysis and treatment selection. The company's growth trajectory reflects expanding adoption of AI-driven oncology tools and increasing demand for personalized cancer treatment protocols. Its competitive positioning centers on its data infrastructure scale and machine learning capabilities applied to complex clinical decision-making. Tempus combines clinical, imaging, and molecular data through AI to provide real-time oncology treatment recommendations at scale across U.S. health systems.
Which company was founded first?
Both SigTuple and Tempus launched in 2015. Same year, but even a few months' head start matters in AI — early movers lock in data, talent, and customer relationships fast.
Which company has more employees?
SigTuple has about 100-500 employees; Tempus has about 2500. A bigger team usually means more revenue or heavier VC backing, but in AI, small teams can build at massive scale.
Are SigTuple and Tempus competitors?
Yes — they're direct rivals. Both SigTuple and Tempus compete in AI Healthcare, targeting many of the same buyers. If you're evaluating one, you should be looking at the other.

Bottom Line

Tempus has a clear lead here — Awaira Score of 84 vs SigTuple's 60. The difference comes down to funding depth and team scale.

Who Should You Watch?

Tempus is in the stronger position — better score and deeper pockets. But SigTuple has room to surprise, especially if they land a marquee investor. Follow both profiles on Awaira to track funding rounds, team changes, and score updates.

Deep Dive